Contact Info

401 N 3rd Street

Hannibal, Missouri 63401-3301

United States

Toll Free Number

1(800) 780-7234

Hotel Direct Number


Hotel Overview

3:00 P.M. CST
11:00 A.M. CST

Welcome to BEST WESTERN On the River!


We are one block up from historic downtown Hannibal and two blocks up from the Mississippi River. The hotel is within walking distance of the Mark Twain boyhood home, museum and riverboat, plus many different bars and restaurants. Bars and restaurants within walking distance include LaBinnah Bistro, The Brick Oven, Mark Twain Brewing Company, Big Muddy BBQ, Java Jive, Christian Ambiance Café, Becky Thatcher's Diner, Mark Twain Dinette, Rumor Has It, Ole Planters Restaurant, Finn's Food and Spirits, and La Azotea Cocktail Lounge.

Downtown also offers a variety of specialty shoppes such as antiques, boutiques, beauty salons, an art gallery, a gelato shop and book stores. There is also a local B7B Theater that opened in 2009. Along with the movie theater Bluff City opened in 2015 and puts on a variety of plays throughout the year. Hannibal has a minor league baseball team called the Cavemen and they host games during the summer at Clemens Field, which is less than a mile from the Best Western On the River. We are also only two miles away from popular tourist attractions like Mark Twain Cave and family fun park Sawyer's Creek.


The Best Western On the River's main building includes an indoor pool and hot tub, exercise room, free high speed fiber internet, river view rooms and a free hot breakfast that includes: eggs, sausage, biscuits and gravy, and a waffle makes. Thirty additional rooms have been added to the Best Western On the River as well. The new building opened in 2015 and is right next door from the main building. All rooms on the second and third floor of the new building have river views. and twenty-four of the thirty rooms offer TWO King beds. The new building also has fiber internet (wired and wireless), its own free hot breakfast, exercise room and guest laundry area. Come Stay with us, and enjoy the attractions America's Hometown has to offer!