7921 Lamar Poole Rd, I-10 @ Exit 50
Biloxi, Mississippi 39532-8724
United States


Toll Free Reservations (US & Canada Only)

Worldwide Numbers

Hotel Direct Number


3:00 P.M. CST


11:00 A.M. CST



Hotel Overview

Stay at this Biloxi, Mississippi hotel featuring deluxe accommodations and southern hospitality.

The Best Western Cypress Creek is conveniently located on the Mississippi Gulf Coast near the popular Casino row and many historic locations around Biloxi. Our hotel offers easy access to recreational opportunities including fishing, beaches and golf. Our hotel guests will also appreciate the variety of nearby dining and shopping options.

Each spacious, well-appointed guest room features all the little extras that make a big difference while traveling such as high-speed wireless Internet access, iron/ironing board, coffee makers, in-room safes, and microwave and refrigerator. Other special hotel amenities include a complimentary deluxe hot breakfast with waffles, omelets and sausages, fitness room, outdoor pool, meeting rooms and banquet facilities.

Whether spending the day sight-seeing or relaxing on the beach, our friendly staff is ready to ensure you a comfortable and memorable stay. Make an online reservation today at our Best Western Cypress Creek in Biloxi, Mississippi. Enjoy your stay.

Hotel Amenities

Because We CareSM

Cleaning Standards

Industry-Leading Cleaning Standards

Modified Breakfast

Modified Breakfast Service & Selections (varies by hotel)

Low Rate Guarantee

Low Rate Guarantee

Hotel Policies

Pet Policy
No pets allowed
Child Policy
Children 16 And Under Are Free In Room With One Paying Adult In Existing Bedding.


Hotel location and the surrounding area

Nearby Attractions

Area Business

  • 5 mile(s) from Brafford O'Keef Funeral, Home
  • 8 mile(s) from Singing River Hospital
  • 15 mile(s) from Ingalls Shipyard
  • 15 mile(s) from Northrup Grumman
  • 18 mile(s) from Chevron Refineries


  • 5 mile(s) from Cruisin' Coast
  • 6 mile(s) from downtown Biloxi
  • 6 mile(s) from Casino Row, casino gambling, more than a dozen casinos on the Gulf Coast
  • 6 mile(s) from Marine Education Center & Aquarium
  • 8 mile(s) from Biloxi Little Theater
  • 8 mile(s) from Kessler Air Force Base
  • 12 mile(s) from Jefferson Davis Home, Jefferson Davis Library, confederate museum, historic cemetery and nature trail
  • 12 mile(s) from Mississippi Coast Coliseum and Convention Center
  • 80 mile(s) from Jazz Fest
  • 90 mile(s) from Mardi Gras
  • 90 mile(s) from site of Super Bowl XXXVI
  • 90 mile(s) from Sugar Bowl


  • .01 mile(s) from Waffle House, American, 24-hour breakfast
  • .01 mile(s) from Domino's Pizza
  • .5 mile(s) from Denny's, American, open for: breakfast, lunch, dinner, open 24 hours
  • .75 mile(s) from McDonald's, Fast Food
  • 3.5 mile(s) from Aunt Jenny's Catfish Restaurant, Seafood
  • 3.5 mile(s) from Anthony's Steak House, Full Service, American
  • 4 mile(s) from Hart'sFried Chicken Buffet
  • 5 mile(s) from Fisherman's Wharf Restaurant, Seafood
  • 5 mile(s) from Germain's Fine Dining
  • 6 mile(s) from Applebee's
  • 6 mile(s) from China Garden, Chinese
  • 8 mile(s) from Jocelyn's, Seafood
  • 8 mile(s) from Catch of the Day, Seafood


  • 10 mile(s) from MGCCC
  • 15 mile(s) from University of South MS

Nearby Cities

  • 6 mile(s) from D'Iberville
  • 15 mile(s) from Gulfport
  • 20 mile(s) from Pascagoula
  • 25 mile(s) from Bay St. Louis
  • 90 mile(s) from New Orleans, LA
  • 70 mile(s) from Mobile


  • 4 mile(s) from several golf courses
  • 5 mile(s) from deep sea fishing
  • 6 mile(s) from Biloxi beaches, boating, jet skiing and scuba diving


  • 5 mile(s) from Edgewater Mall
  • 10 mile(s) from Outlet Mall


  • 8 mile(s) from Greyhound, bus terminal
  • 12 mile(s) from Amtrak, train station
  • 16 mile(s) from Trent Lott International
  • 90 mile(s) from New Orleans International