Greenville sits along Interstate 70 in south-central Illinois between St. Louis and Effingham, a college town built around Greenville University and a courthouse square. The SureStay by Best Western Greenville makes a comfortable base in Greenville, Illinois, close to the university, the historic square, the DeMoulin museum, and the highway between St. Louis and Effingham.
Halfway down Interstate 70 between St. Louis and Effingham, the hotel makes an easy overnight. A free breakfast is in the morning, the rooms hold a flat-screen TV, microwave, and refrigerator, and free parking sits right outside. Greenville University and the quirky DeMoulin Museum of fraternal-lodge gadgets anchor the small college town. Carlyle Lake, the largest lake in Illinois, spreads a short drive south of Greenville for boating.
Highway convenience and campus events, the square, and St. Louis beyond all sit close by. Settle in and let south-central Illinois set the pace.