Hotel Details
120 S Interstate Drive, Sikeston, Missouri 63801-8641 United States

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Hotel Overview

Welcome to a stay that blends comfort with a genuine sense of place in southeast Missouri. Best Western Plus Sikeston offers a warm, inviting experience for travelers who appreciate convenience and a touch of local personality. Its location off of Interstate 55 in Sikeston places you close to the attractions, flavors, and traditions that make this community memorable, creating the perfect starting point for your visit.

Best Western Plus Sikeston sits near Lambert’s Cafe, one of the most iconic stops in the region, along with shopping centers, outdoor attractions, and major local employers. Guests often find themselves perfectly positioned to enjoy beloved events, including the Sikeston Jaycee Bootheel Rodeo, the Dogwood Azalea Festival, and seasonal celebrations that bring the town to life. With easy access for road travelers, families exploring southeast Missouri, and business guests visiting the area, the hotel serves as a convenient hub for all types of stays.

Inside the hotel, guests can enjoy thoughtful amenities designed for comfort and productivity. Begin each morning with a free hot breakfast before heading out. Relax in the indoor pool, stay energized in the fitness center, or take advantage of business-friendly features that support work on the go. Spacious rooms offer modern comforts and room to unwind after a day of travel, meetings, or local experiences.

Best Western Plus Sikeston is a modern hotel located off Interstate 55 in Sikeston, Missouri, near Lambert’s Cafe, shopping, and local employers, offering spacious rooms, free hot breakfast, an indoor pool, a fitness center, and business-friendly amenities for leisure and business travelers.

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Hotel Amenities

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Location

Hotel location and the surrounding area

120 S Interstate Drive
Sikeston, Missouri

Nearby Attractions

Area Business

  • 0.05 mile(s) from Steward Steel, 101 N. Interstate Drive, Sikeston, MO. 573-471-2121
  • 0.05 mile(s) from FedEx® Shipping Center, 2830 E Malone, Sikeston, MO.
  • 2.00 mile(s) from Tetra Pak®, 2200 E. Malone Avenue, Sikeston, MO. 573-471-1441
  • 4.00 mile(s) from Unilever® South Plant, 1000 County Line Road Sikeston, MO. 573-471-7051
  • 5.00 mile(s) from Cott Beverage, 301 Larcel Drive, Sikeston, MO 573-471-4445
  • 6.00 mile(s) from Atlas Cold Storage, 2500 Rose Parkway, Sikeston, MO 573-471-7727
  • 6.00 mile(s) from Americold® Logistics, 2500 Rose Parkway, Sikeston, MO. 573-471-7727
  • 6.00 mile(s) from Missouri Department of Tr, 2675 N. Main Street, Sikeston, MO. 573-472-5333
  • 6.00 mile(s) from Do it Best, 2600 Rose Parkway, Sikeston, MO. 573-472-5770
  • 6.00 mile(s) from Unilever® North Plant, 2400 Rose Parkway, Sikeston, MO.
  • 6.00 mile(s) from Cargill®, 410 W. Malone Avenue, Sikeston, MO. 573-472-2272
  • 7.00 mile(s) from Orgill, 2727 N. Main Street, Sikeston, MO. 573-471-2071
  • 8.00 mile(s) from Alan Wire, 814 S. West Street, Sikeston, MO. 573-471-9548
  • 20.00 mile(s) from Tyson® Foods, 1001 E. Stoddard Street, Dexter, MO.

Attractions

  • 3.00 mile(s) from The Sikeston Depot Museum, 116 W Malone, Sikeston. Housed in the city's historically renovated train depot on one of the first rail lines constructed west of the Mississippi River, the depot features a historic museum recounting the most important aspect of the area's culture; an art gallery in which local artists display their work; and a cultural center displaying traveling exhibits from national museums. Free Admission.
  • 7.00 mile(s) from Southeast Missouri Agricultural Museum and Granny's Antiques, County Road 521, Bertrand, MO. 6,000 plus pieces of antique farm equipment. Indoor display areas include main museum and five outer buildings of great historic interest, including two Missouri log cabins (circa 1880), one wooden railroad caboose, one related railroad depot, and a reconstructed 1920's service station.
  • 4.00 mile(s) from The Columns, N. New Madrid Street, Downtown. These six majestic pillars stand as a monument to the city's religious heritage and the beautiful First Methodist Church, which was erected in 1879 and tragically destroyed by fire in 1968. This church's congregation represented the first Methodist church west of the Mississippi River.
  • 3.00 mile(s) from Jaycee Bootheel Rodeo, 1220 N Ingram Rd, Sikeston, MO 63801. Join the Jaycee Bootheel Rodeo in August for the PRCA sanctioned rodeo. The largest in the state and one of the largest in the USA. Hosts nationally known country music nightly.

Dining

  • 1.00 mile(s) from Lambert's Cafe, cafe, American, open for: lunch, dinner, The only home of the throwed rolls®. Try some of Lambert's favorite, pass-arounds. Throwed Rolls, Sorghum Molasses, Black-eyed Peas, Fried Okra, Macaroni & Tomatoes and Fried Potatoes. Open seven days a week from 10:30 a.m. to 9 p.m.
  • 1.00 mile(s) from El Tapatio, bar/lounge, Mexican, open for: lunch, dinner, Monday-Saturday 11 a.m. to 10 p.m. and Sunday 11 a.m. to 9:30 p.m.
  • 0.50 mile(s) from Ruby Tuesday, full service, American, open for: lunch, dinner
  • 4.00 mile(s) from China Buffet, buffet, Chinese, open for: lunch, dinner, largest selection and best prices in town. Dinner buffet: catfish, fried shrimp, frog legs.
  • 3.00 mile(s) from Grecian Steak House, buffet, American, open for: lunch, dinner, numerous item salad and dessert bar. Hot food bar, ice cream and sundae bar. All free with dinner.
  • 4.00 mile(s) from Kirby's Sandwich Shop, cafe, American, open for: lunch, since 1907. Burger baskets, etc. In our historic downtown area. Mom & Pop style cafe.
  • 4.00 mile(s) from Susie's Bake Shoppe, cafe, American, open for: lunch, homemade bakery products. Daily specials. Fresh baked desserts. Fitness selections. In our historic downtown area.
  • 4.00 mile(s) from Applebee's®, full service, American, open for: lunch, dinner
  • 4.00 mile(s) from Jeremiah's, full service, American, open for: lunch, dinner, fine dining and spirits. In our historic downtown area.
  • 2.00 mile(s) from Cheers Bar & Grill, Inc., bar/lounge, American, open for: lunch, dinner, also has an area for families that don't want to eat in the bar/grill area.
  • 3.00 mile(s) from Dexter Bar-B-Que, cafe, American, open for: lunch, dinner
  • 3.00 mile(s) from Jay's Krispy Fried Chicken, cafe, American, open for: breakfast, lunch, dinner, one of the two main breakfast cafes in town.
  • 2.50 mile(s) from Pizza Hut®, full service, American, open for: lunch, dinner, hours Sunday-Thursday 11 a.m. to 10 p.m. and Friday and Saturday 10 a.m. to 11 p.m.
  • 1.50 mile(s) from Pizza Inn®, buffet, American, open for: lunch, dinner

Education

  • 3 mile(s) from Three Rivers Community College
  • 8 mile(s) from Southeast Missouri State, four year university

Nearby Cities

  • 13.00 mile(s) from Charleston
  • 53.00 mile(s) from Poplar Bluff
  • 55.00 mile(s) from Caruthersville
  • 60.00 mile(s) from Paducah, Kentucky
  • 60.00 mile(s) from Perryville
  • 65.00 mile(s) from Blytheville, Arkansas
  • 70.00 mile(s) from Metropolis, Illinois
  • 140 mile(s) from St. Louis
  • 150 mile(s) from Memphis, Tennessee
  • 13.00 mile(s) from Benton
  • 265 mile(s) from Branson
  • 20.00 mile(s) from New Madrid
  • 20.00 mile(s) from Dexter
  • 30.00 mile(s) from Cape Girardeau
  • 40.00 mile(s) from Jackson

Recreation

  • 2 mile(s) from Recreation Complex, The City's most complete outdoor recreational facility, it offers mobility accessible playground equipment, a tot lot for preschool children, lighted tennis courts, sand volleyball courts, horseshoe pits, soccer fields, unlighted T-ball fields, lighted softball fields, a lighted Junior Babe Ruth baseball field, an outdoor basketball court, 4.6 acre fishing lake, half-mile fitness trail, picnic shelters with charcoal grills, drinking fountains, and restroom facilities.
  • 2 mile(s) from Sikeston Country Club, Tee off at one of the finest county club courses in Southeast Missouri. The Sikeston Country Club features an 18 hole, 71 par, semi-private golf course with pro shop. East Malone, Sikeston
  • 2 mile(s) from Sikeston Blowing Center, 1601 East Malone Sikeston 573-471-2430
  • 2.5 mile(s) from Malco Trio Cinema, 1045 East Malone in the Midtowner Shopping Center. 573-471-8420
  • 3.5 mile(s) from YMCA, 511 Taylor Street, Sikeston Facilities include a fitness center, an aquatic center that has a 6-lane pool, 15 foot high water slide, a three-lane wide walking track, a gymnasium used for basketball and volleyball, nursery, locker rooms and sauna.

Shopping

  • 0.50 mile(s) from Sikeston Factory Outlet, Kitchen Collection®, Famous Footwear®, 50 Off, Carter's®, VF® Outlet, Rue 21®, G.H. Bass & Co.®, Fashion Nails, dressbarn®, L'eggs, Hanes®, Bali® & Playtex®
  • 1.50 mile(s) from Judy's Fashions, 2107 East Malone, Sikeston. Family clothing store and consignment shop.
  • 2.00 mile(s) from Factory Connections, Malone Avenue, Sikeston. Men's & women's clothing store.
  • 4.00 mile(s) from Walmart® Superstore, South Main, Sikeston.
  • 4.00 mile(s) from Cato, South Main, Sikeston. Women's clothing store.
  • 3.50 mile(s) from Sikes Sporting Goods, 207 North New Madrid Street, Sikeston.
  • 4.00 mile(s) from JC Penney®, 1215 South Main, Sikeston.
  • 4.00 mile(s) from Goody's, South Main, Sikeston. Family clothing store.

Transportation

  • 154 mile(s) from St Louis Lambert International Airport
  • 56.00 mile(s) from Barkley Regional Airport
  • 4.00 mile(s) from Sikeston Memorial Municipal Airport

Frequently Asked Questions

Q. Does the Best Western Plus Sikeston offer breakfast?
The Best Western Plus Sikeston includes a free breakfast, served daily.
Q. Is the Best Western Plus Sikeston Pet Friendly?
We are Pet Friendly and allow up to two dogs in a limited number of rooms. The size limit for any one dog shall be 80 pounds. Other pet types (e.g., cats) may be allowed upon the hotel’s approval prior to arrival. The Pet Friendly rate is 25.00 USD per day.
Q. What time is Check-in at the Best Western Plus Sikeston?
Check-in time at the Best Western Plus Sikeston is 3:00 P.M.
Q. What time is Check-out at the Best Western Plus Sikeston?
Check-out time at the Best Western Plus Sikeston is 11:00 A.M.
Q. Does the Best Western Plus Sikeston have free Wi-Fi?
Yes, we offer free Wi-Fi throughout the hotel and all guest rooms.  
Q. Does the Best Western Plus Sikeston have a pool?
Yes, enjoy our indoor swimming pool on premises.
Q. Does the Best Western Plus Sikeston have a fitness center?
Yes, the Best Western Plus Sikeston is pleased to offer guests a fitness center/health club