Hotel Details
120 S Interstate Drive, Sikeston, Missouri 63801-8641 United States

Hotel Overview

Located just off Interstate 55 in Sikeston, this hotel provides convenient access to many of the area's best-known attractions, local employers, shopping, and dining. Guests are close to Lambert's Cafe, the Sikeston Jaycee Bootheel Rodeo, the Dogwood Azalea Festival, and other community events that showcase the character of southeast Missouri.

Guests can start the day with a free hot breakfast before heading out to explore the area or attend meetings. The hotel features spacious guest rooms, an indoor pool, fitness center, and business-friendly amenities designed for both leisure and business travelers. Whether passing through or spending time in the region, the hotel offers a comfortable and convenient place to stay.

Guest Rooms

Popular rooms offered at this hotel.

View All Rooms

Hotel Amenities

Hotel Policies

Location

Hotel location and the surrounding area

120 S Interstate Drive
Sikeston, Missouri

Nearby Attractions

Area Business

  • 2.90 mile(s) from Montgomery Bank, family-owned Missouri bank founded in 1934, headquartered in downtown Sikeston.
  • 0.05 mile(s) from FedEx® Shipping Center, 2830 E Malone, Sikeston, MO.
  • 2.90 mile(s) from Missouri Delta Medical Center, regional not-for-profit hospital and major area employer serving southeast Missouri.
  • 5.40 mile(s) from Unilever Ice Cream Plant (Magnum), a operated ice cream manufacturing facility, a major regional employer.
  • 5.40 mile(s) from Orgill, Inc., regional distribution hub. One of the largest independent hardware distributors in North America.

Attractions

  • 3.40 mile(s) from Sikeston Depot Museum & Cultural Center, free 1916 restored rail depot museum with local history, rail heritage, and rotating art displays.
  • 3.00 mile(s) from Missouri Plain Folk Gallery, community gallery showcasing regional folk artists and agricultural-heritage paintings.
  • 4.00 mile(s) from Malco Sikeston Cinema Grill, modern first-run movie theater with rocking seats, dine-in concessions, and arcade.
  • 2.30 mile(s) from Sikeston Jaycee Bootheel Rodeo Grounds, home of the annual Bootheel Rodeo, drawing over 40,000 visitors with rodeo, concerts, and festivals.

Dining

  • 0.90 mile(s) from Lambert's Cafe, casual dining, American, Sunday 10:00 a.m. to 9:00 p.m., Monday 10:30 a.m. to 9:00 p.m., Tuesday 10:30 a.m. to 9:00 p.m., Wednesday 10:30 a.m. to 9:00 p.m., Thursday 10:30 a.m. to 9:00 p.m., Friday 10:30 a.m. to 9:00 p.m., Saturday 10:00 a.m. to 9:00 p.m., iconic 'Home of the Throwed Rolls' — hearty comfort food with roving side-dish carts. Sikeston is where the magic of Lambert's started before spreading to Ozark, MO and Foley AL.
  • 2.90 mile(s) from Grecian Steak House, casual dining, Steakhouse, Sunday 10:30 a.m. to 9:00 p.m., Monday 10:30 a.m. to 9:00 p.m., Tuesday 10:30 a.m. to 9:00 p.m., Wednesday 10:30 a.m. to 9:00 p.m., Thursday 10:30 a.m. to 9:00 p.m., Friday 10:30 a.m. to 9:00 p.m., Saturday 10:30 a.m. to 9:00 p.m., long-running, locally owned steakhouse with a well-stocked salad bar and fried catfish.
  • 1.80 mile(s) from Bo's Breakfast and Bar-B-Q, casual dining, Bbq, Sunday 7:00 a.m. to 2:00 p.m., Monday 6:00 a.m. to 2:00 p.m., Tuesday 6:00 a.m. to 2:00 p.m., Wednesday 6:00 a.m. to 2:00 p.m., Thursday 6:00 a.m. to 2:00 p.m., Friday 6:00 a.m. to 7:00 p.m., Saturday 6:00 a.m. to 2:00 p.m., local breakfast and barbecue spot with made-to-order biscuits, gravy, and smoked meats.
  • 4.00 mile(s) from Susie's Bake Shoppe, cafe, American, open for: lunch, homemade bakery products. Daily specials. Fresh baked desserts. Fitness selections. In our historic downtown area.
  • 2.80 mile(s) from Dexter Bar-B-Que, casual dining, Bbq, Sunday closed, Monday 11:00 a.m. to 8:00 p.m., Tuesday 11:00 a.m. to 8:00 p.m., Wednesday 11:00 a.m. to 8:00 p.m., Thursday 11:00 a.m. to 8:00 p.m., Friday 11:00 a.m. to 8:00 p.m., Saturday 11:00 a.m. to 8:00 p.m., genuine Southeast Missouri pit-smoked barbecue since 1983, dry-rubbed and slow-cooked for hours, served with regional tangy vinegar sauce in a warm, welcoming local institution.
  • 4.00 mile(s) from Applebee's®, full service, American, open for: lunch, dinner
  • 2.80 mile(s) from Jay's Krispy Fried Chicken, casual dining, American, Sunday 6:00 a.m. to 9:00 p.m., Monday 6:00 a.m. to 9:00 p.m., Tuesday 6:00 a.m. to 9:00 p.m., Wednesday 6:00 a.m. to 9:00 p.m., Thursday 6:00 a.m. to 9:00 p.m., Friday 6:00 a.m. to 9:00 p.m., Saturday 6:00 a.m. to 9:00 p.m., a Bootheel favorite for crispy, golden fried chicken, dished up fast in a casual, no-fuss setting locals have trusted for generations.
  • 0.20 mile(s) from El Bracero, casual dining, Mexican, Sunday 11:00 a.m. to 9:30 p.m., Monday 11:00 a.m. to 10:00 p.m., Tuesday 11:00 a.m. to 10:00 p.m., Wednesday 11:00 a.m. to 10:00 p.m., Thursday 11:00 a.m. to 10:00 p.m., Friday 11:00 a.m. to 11:00 p.m., Saturday 11:00 a.m. to 10:30 p.m., vibrant Mexican fare where sizzling fajitas and fresh margaritas bring bold Southeast Missouri flavor to your table in a lively, colorful dining room guests keep coming back to.

Education

  • 29.30 mile(s) from Southeast Missouri State University, public four-year university in Cape Girardeau with over 10,000 students.
  • 54.00 mile(s) from Three Rivers College, two-year public college in Poplar Bluff serving a four-county region.

Nearby Cities

  • 11.00 mile(s) from Charleston, small Bootheel town known for its historic downtown and the annual Dogwood-Azalea Festival.
  • 21.10 mile(s) from Cairo, historic river town at the confluence of the Mississippi and Ohio Rivers.
  • 21.20 mile(s) from New Madrid, a Mississippi River town known for the New Madrid Historical Museum and 1811-12 earthquake history.
  • 24.00 mile(s) from Dexter, a Bootheel town roughly midway between Sikeston and Poplar Bluff.
  • 29.00 mile(s) from Cape Girardeau, regional hub city with a historic downtown riverfront, Southeast Missouri State University, and the Crisp Museum.
  • 48.00 mile(s) from Poplar Bluff, 'Gateway to the Ozarks', home to Three Rivers College and the regional Amtrak station.
  • 13.00 mile(s) from Benton
  • 265 mile(s) from Branson

Recreation

  • 2.10 mile(s) from Sikeston Recreation Complex, a 196-acre city complex with a stocked fishing lake, skate park, sports fields/courts, and the Cottonbelt Trail.
  • 2.90 mile(s) from Sikeston YMCA, full-service YMCA with pool, gym, indoor track, and basketball courts.
  • 4.10 mile(s) from Sikeston Park (Lincoln Memorial), neighborhood park with splash pad, playground, and covered picnic shelters.

Shopping

  • 1.50 mile(s) from Judy's Fashions, 2107 East Malone, Sikeston. Family clothing store and consignment shop.
  • 2.00 mile(s) from Factory Connections, Malone Avenue, Sikeston. Men's & women's clothing store.
  • 4.00 mile(s) from Walmart® Superstore, South Main, Sikeston.
  • 4.00 mile(s) from Cato, South Main, Sikeston. Women's clothing store.
  • 3.50 mile(s) from Sikes Sporting Goods, 207 North New Madrid Street, Sikeston.
  • 0.30 mile(s) from Sikeston Factory Outlet Stores, a locally loved flea market bursting with antiques, toys, and treasures — perfect for guests who love to browse and explore.

Transportation

  • 152.00 mile(s) from Memphis International Airport
  • 29.00 mile(s) from Cape Girardeau Regional Airport
  • 2.10 mile(s) from Sikeston Memorial Municipal Airport
  • 9.00 mile(s) from Greyhound Bus Stop (Matthews, MO)
  • 48.00 mile(s) from Poplar Bluff Station (Texas Eagle line)

Frequently Asked Questions

Q. Does the Best Western Plus Sikeston offer breakfast?
The Best Western Plus Sikeston includes a free breakfast, served daily.
Q. Is the Best Western Plus Sikeston Pet Friendly?
We are Pet Friendly and allow up to two dogs in a limited number of rooms. The size limit for any one dog shall be 80 pounds. Other pet types (e.g., cats) may be allowed upon the hotel’s approval prior to arrival. The Pet Friendly rate is 25.00 USD per day.
Q. What time is Check-in at the Best Western Plus Sikeston?
Check-in time at the Best Western Plus Sikeston is 03:00 P.M.
Q. What time is Check-out at the Best Western Plus Sikeston?
Check-out time at the Best Western Plus Sikeston is 11:00 A.M.
Q. Does the Best Western Plus Sikeston have free Wi-Fi?
Yes, we offer free Wi-Fi throughout the hotel and all guest rooms.  
Q. Does the Best Western Plus Sikeston have a pool?
Yes, enjoy our pool
Q. Does the Best Western Plus Sikeston have a fitness center?
Yes, the Best Western Plus Sikeston is pleased to offer guests a fitness center/health club